2024 SASCO Symposium
2024 SASCO Symposium
2024 SASCO RESEARCH SYMPOSIUM
Center for Systems Analysis of Stress-adapted Cancer Organelles
July 23, 2024 – University of Virginia, Charlottesville, VA
8:15 Breakfast [Pinn Hall Conference Center-1st floor Lobby]
9:00 Welcome & Overview – Matthew Lazzara & Kevin Janes (Center MPIs) [PHCC-Auditorium]
9:15 Model systems to represent diverse populations – Kristen Naegle [PHCC-Auditorium]
9:30 Keynote: “Harnessing Chemical Interactions to Explore Tumor Cell Biological Responses to Fluctuations in Metal and Micronutrient Availability” – Donita Brady, University of Pennsylvania [PHCC-Auditorium]
10:30 Coffee Break [PHCC-1st floor Lobby]
10:45 Project 1 (Breast Cancer/Spindle-assembly checkpoint, repair) [TBA]
- Introduction, Todd Stukenberg (Project Co-Lead)
- “Systems modeling of mitotic signaling during chromosome segregation in breast epithelia” – Catalina Alvarez
- “Modeling state transitions and phase separation of mitotic condensates” – Sarah Groves
11:30 Project 2 (Colon Cancer/Mitochondrial fragmentation) [TBA]
- Introduction, David Kashatus (Project Co-Lead)
- “Reconciling Predictions of Cancer Gene Essentiality: Bridging the Genotype-Phenotype Gap” – William Shao
- “Mechanisms linking Drp1 and mitochondrial fission to tumor growth in KRas-driven colon cancer” – Daniel Phipps
12:15 Lunch [PHCC]
1:30 Project 3 (Glioblastoma/Membranes) [TBA]
- Introduction, Benjamin Purow (Project Co-Lead)
- “Overexpression of EGFR in glioblastoma cells promotes a vacuolized phenotype consistent with methuosis” – Sarah Buchanan
- “Assessing methods to evaluate EGFR-associated plasma membrane stress” – Adrian Shimpi
2:15 Lightning Talks from Selected Posters [TBA]
2:30 Poster Session [PHCC-2ABC]
4:00 Career Trajectories Panel Discussion [MEB 3110]
4:45 Social Hour [MR5-2nd floor Lobby]
3:30 EAB Confers [MR5-2005]
4:30 EAB Talks with MPIs [MR5-2005]
5:00 MPIs Debrief NCI on discussion with EAB [MR5-2005]
