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Samuel Presman

Leanne Mahraj

RIPTiDe integrates transcriptomic data with a model to reveal metabolic differences between wildtype and mutated KRAS samples.

Mariah Snelson

Data collection techniques and image analysis for the study of glioblastoma multiforme and pancreatic ductal adenocarcinoma progression.

Joseph Guillen

Seth Boehringer

Bryan Rangel Valle

Riko Mukoyama

Iylan Howson

Olga Buhlak

A project under the SASCO umbrella focusing on studying the effect, and ultimately mechanism by which mitochondrial morphology and topology influences the distribution of proteins within the cell. My role in the project is to work with mitochondrial immunofluorescence data in order to develop a meaningful way to quantitatively describe mitochondrial morphology and topology, ultimately aiming to develop a set of features that can serve as a mitochondrial “fingerprint” for cell lines with distinct mitochondrial networks.

George Marshall

Treating glioblastoma cells with Prozac and chloroquine, then measuring effect on cell count.

Rose Olumuyide

My project will investigate how CCNF regulates FOXM1 activation throughout the cell cycle by combining protein measurements with transcriptional snapshots and computational modeling. First, I’ll synchronize cells at key cycle phases and directly quantify Foxm1 and Cyclin F protein levels at each stage. Next, I’ll use RNA-seq data from those synchronized cultures—and from breast cancer samples—to infer stage-specific FOXM1 transcriptional activity. Finally, I’ll map those activity profiles onto a model to reveal how CCNF-driven timing shapes FOXM1 dynamics and downstream regulatory programs.

Calum Dudgeon

Sarah Groves

Sarah Groves developed the first of three videos designed to introduce clinicians to systems concepts and approaches.

Watch the Video here.

• Multiple meetings with Todd Stukenberg to brainstorm and outline first video
• Met with BJ Purrow (MD/PhD Project 3) to discuss challenges/goals of working with MDs
• Established collaborations with Cimona Hinton to provide feedback for each of the stages of the video

Rusty Hawes

Rusty Hawes will develop the second of three videos designed to introduce clinicians to systems concepts and approaches.

Cimona Hinton

Our first scholar-in-residence collaborator, Cimona Hinton, PhD is featured in this UVa School of Medicine article.

Nakea Pennant

Lecia Robinson, PhD

Lecia Robinson PhD, our second scholar-in-residence collaborator, worked in the Kashatus Project 2 Lab.

Christopher Bolden, PhD