The Resource Management Teamacts as the interface between the MC2 Center Research Coordinating Hub and the specific resource-development activities of the SASCO Center. The group i) ensures standards and platforms put forth by the Resource and Data Sharing Working Group are transmitted to the Center, ii) communicates Center-specific challenges with resource sharing to the MC2 Center, and iii) facilitates the timely sharing of data and resources originating from the High-Content Imaging & Analysis Core and the Research Projects.
The SASCO Center offers Intra-Center Pilot Projects with cost-matched support from the UVA Comprehensive Cancer Center and UVA Office of the Vice-President for Research. Details on the Intra-Center Pilot Projects are released as an annual Request For Applications.
Request for applications to our Pilot Grant Program: The Systems Analysis of Stress-Adapted Cancer Organelles (SASCO) Center is a newly activated NCI-funded U54 Cancer Systems Biology Consortium (CSBS) research center at UVA dedicated to studying the adaptations of cancer cell organelles to oncogenic stresses. SASCO investigators are organized into three research groups focusing on: 1) The chromosome passenger complex in breast cancer; 2) Mitochondrial stress in colon cancer; and 3) Abnormal macropinocytosis (methuosis) in glioblastoma. The research groups are supported by a high-content imaging and image analysis research core. For more information and to apply via InfoReady, click here.
- Application due Nov. 7, 2022 at 5 p.m.
More details on the Cross-Consortium Projects within the Cancer Systems Biology Consortium will be reported in Year 2 of the SASCO Center.
The Leadership Team is the organizing body for Center-level planning and decision-making. The group i) monitors progress toward milestones in the Plan to Enhance Diverse Perspectives, ii) reviews intracenter pilot projects, iii) plans annual site visits with NCI staff and the External Advisory Board, and iv) discusses candidate cross-consortium projects in consultation with the NCI.
The SASCO Center is committed to increasing inclusion of scientists from historically marginalized backgrounds and introducing antiracist research practices within its research activities. We will take proactive steps to recognize and lower the systematic barriers that have led to marginalization of certain groups in cancer research. We utilize the pilot funding mechanism, coupled with proactive outreach and mentorship to increase representation and support career success of women and members of historically marginalized backgrounds. Additionally, we seek to improve research awareness within the Center about how institutionalized racism has resulted in white-centered experimental systems and bias in conventional citation practices. The Administrative Core supports an annual event that includes community members and couples with summer activities of the Outreach Core as part of its Plan to Enhance Diverse Perspectives.
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